Protein Details: Aquaporin Z
Protein ID
ICDB_Pro_0693
Protein Name
Aquaporin Z
Gene Name
aqpZ; slr2057
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
247 amino acids
AlphaFoldDB
AF-P73809-F1-model_v4.pdb
Function
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
Sequence
MKKYIAEFIGTFWLVLGGCGSAVFAAFIAAPGGGNTNEFGLGYLGVALAFGLTVFTGAYALGHISGGHFNPAVSFGLWMGKRFPGSQLAPYIGAQVLGAIVASLFIFIVAQGGPNFSLDGSNPLATNGFGDHSPQGYGFLAALLIEFVLTFIFLIVILGVTDKTAPAGFAPAAIGLALTLIHLISIPITNTSVNPARSTGVALFCGNPALIGQLWLFWLAPIAGALLAGFVYHNVLEDLGRPEPEAE
PDB Structures
Ligand Binding
Binding Site
SITE 19: "Involved in tetramerization or stability of the tetramer"; SITE 50: "Selectivity filter"; SITE 182: "Selectivity filter"; SITE 191: "Selectivity filter"; SITE 197: "Selectivity filter"
Disease
Location
DOI ID
10.1093/dnares/3.3.109